Page 23 - IB April 2023
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ALLERGY  •  INTOLERANCE  •  CELIAC  •  PCR
                                   ARVEEN CHANDRA I VANMED LABS I FIJI


        ALLERGY-  Allergy IgE panel is an  in vitro  diagnostic  test in  the   test designed for the qualitative detection of antibodies (IgA/IgG/IgM)
       qualitative determination of allergen IgE concentrations in human   against human tissue transglutaminase in whole human blood.
       serum/plasma using immunoblotting technique.            PCR- The GeneXpert Instrument Systems automate and integrate
        A multiplex allergy diagnostic kit, based on the principle of enzyme   sample preparation, nucleic acid extraction and amplification, and
       immunoassay includes  nitrocellulose  membranes  having  various   detection of the target sequences in simple or complex samples using
       allergens absorbed at regular interval lines, which makes it possible to   real-time PCR assays. The sensitivity of the Xpert Xpress SARS-CoV-2
       test 107 specific allergens in one test.             assay was found to be 100% (20 of 20) and the specificity was 80% (16
        The World Allergy Organisation’s (WAO) estimate of allergy   of 20).
       prevalence of the whole population by country ranges between 10
       – 40% (Pawankar R, et al, 2013). Allergy is a very common ailment,
       affecting more than 20% of the population of most developed countries
       (Pawankar R, et al, 2013).
        INTOLERANCE- Protia Food IgG is an in vitro diagnostic test with
       semi-quantitative determination of food specific IgG (sIgG) in human
       serum using immunoblotting method. In general, the intestine only
       absorbs nutrients. Bacteria, viruses, and food decomposition elements
       do not absorb into the body due to its dense composition (tight junction).
       However, when the dense structure of the intestine is damaged and
       becomes “leaky gut”, the food decomposition elements penetrate into
       the blood. This makes our body’s immune system recognize the food
       decomposition factor as an external harmful factor, causing an immune
       sensitive reaction.
        Understanding the difference between food allergies and food
       intolerances can leave a person justifiably confused. With these medical
       conditions having potential overlapping symptoms (e.g., cramps, upset
       stomach, diarrhea, skin rash, and headache), it is easy to see why the line
       separating the two is so often blurred.
        Food allergy (also called hypersensitivity) involves an inappropriate
       immune reaction to a seemingly harmless, non-pathogenic substance.
       The body reacts to the substance as if it were fighting a disease-producing
       microorganism. In contrast to food allergy, food intolerance does not
       involve the body’s immune system. Intolerance is an adverse reaction to
       a food, likely to originate in the gastrointestinal system, usually caused
       by a limited ability or an inability to digest or absorb certain foods or
       their components.
        CELIAC- Celiac is characterized by inflammation of the small bowel,
       triggered by exposure to gluten.  IgA is mediated antibodies directed
       against tissue transglutaminase. Celiac Disease is an enteropathy caused
       by a permanent intolerance to gluten and specifically to gliadin, one of its
       protein fragments. The Celiac Quick Test is an immunochromatographic



                  FOOD ALLERGY - 107 ALLERGENS = $150
                 FOOD INTOLERANCE - 50 ALLERGENS = $150

                        CELIAC - GLUTEN = $485
           ALLERGY  +  FOOD INTOLERANCE  +  CELIAC   =     $350 PACKAGE
           107 ALLERGENS  60 ALLERGENS   CELIAC
                               PCR
                      NORMAL - $150 (Results-12hrs)
                      URGENT - $250 (Results-4hrs)
                  EXTREMELY URGENT - $300 (Results-1hr)


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